Signal Transduction: IMPlications for Ras-Dependent ERK Signaling
نویسندگان
چکیده
Ras interacts with numerous downstream effectors to transmit a diverse array of cellular signals. A new study shows that a protein known as Impedes Mitogenic signal Propagation, IMP, is an E3 ubiquitin ligase that binds Ras and modulates MAP kinase signaling by regulating the scaffolding activity of KSR.
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ورودعنوان ژورنال:
- Current Biology
دوره 14 شماره
صفحات -
تاریخ انتشار 2004